Cardiac surgery (Adult)

We conduct a wide range of studies in adult cardiac surgery, some look at drug interventions that may be applied before, during or after cardiac surgery.  This could take the form of fluid replacement immediately prior to surgery, medication added to the cardiopegia solution used to stop the heart during surgery or insulin control of glucose levels during or after surgery.

We also have a large portfolio of work studying non-drug intervention. For example, one study is comparing alternative methods of taking the vein for grafting and testing its viability. These studies aim to improve outcomes after cardiac surgery mainly using interventions during the operation, although some interventions may be applied shortly before the operation or during the patient’s hospital stay afterwards.

Cardiac surgery (Paediatric)

The paediatric cardiac surgery studies are designed to improve outcomes after cardiac surgery for congenital heart conditions, and are important as evidence gathered in adult cardiac surgery trials cannot always be extrapolated to children. 


Our cardiology portfolio is diverse, ranging from studies looking at the best way to diagnose cardiac disease to management of drug therapy after treatment for a blocked coronary artery using angioplasty. 

Emergency medicine

Trials of interventions to be used in emergency care settings, such as equipment or treatment used in ambulances in the management of cardiac arrests. 


General surgery

Our general surgery studies include comparing different surgical methods (e.g. different types of bariatric surgery for the management of morbid obesity) or comparing aspects of the care of surgical patients (e.g. the use of wound dressings in abdominal and obstetric surgery). 


These observational studies look at the results without influencing the treatment that the participants receive. 


Our ophthalmology studies mainly focus on the treatment and management of neovascular Age related Macular Degeneration, the most common type of blindness in the over 50s.  Studies include looking at the best treatment regimen, and whether the disease requires hospital consultant care or can be managed by community optometrists. 

Respiratory Medicine 

Our study in respiratory medicine looks at the thickening of the lungs casued by asbestos, and the best ways to scan for cancer. 

Thoracic Surgery

Our studies into thoracic surgery specialises in the treatment of chest diseases, such as lung cancer,


This section documents studies which the CTEU have coordinated, which have now finished. 

Participating In

Information on trials which Research Nurses are taking part in, but the CTEU is not the leading coordinating centre.